Rare association between ankylosing spondylitis and paget's disease: A case of pagetic vertebral ankylosis

Celil Barlas Cengiz; Melih Kızıltepe; Hüseyin Kaplan; Emel Oğuz Kökoğlu; Tuğba Kahraman Denizhan; Abdurrahman Soner Şenel

doi:10.1007/s11657-024-01490-4

Rare association between ankylosing spondylitis and paget's disease: A case of pagetic vertebral ankylosis

Arch Osteoporos. 2024 Dec 27;20(1):3. doi: 10.1007/s11657-024-01490-4.

Authors

Celil Barlas Cengiz¹, Melih Kızıltepe², Hüseyin Kaplan³, Emel Oğuz Kökoğlu², Tuğba Kahraman Denizhan², Abdurrahman Soner Şenel²

Affiliations

¹ Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Erciyes University, 38030, Kayseri, Turkey. [email protected].
² Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Erciyes University, 38030, Kayseri, Turkey.
³ Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

PMID: 39725805
DOI: 10.1007/s11657-024-01490-4

Abstract

Paget's disease is a condition marked by abnormal bone remodeling, involving both excessive bone formation and destruction, predominantly in the elderly. Pagetic vertebral ankylosis is a rare manifestation, often associated with Paget's disease, ankylosing spondylitis, or diffuse idiopathic skeletal hyperostosis. This form of acquired vertebral ankylosis is uncommon and occurs in cases with bone-bridging syndesmophytes or osteophytes. Here, we present a case of delayed diagnosis of Paget's disease in the lower vertebral column, progressing to cervicothoracic vertebral ankylosis secondary to ankylosing spondylitis.

Keywords: Ankylosing spondylitis; Bone remodeling; Pagetic vertebral ankylosis; Paget’s disease.

Publication types

Case Reports

MeSH terms

Ankylosis / diagnostic imaging
Ankylosis / etiology
Humans
Osteitis Deformans* / complications
Osteitis Deformans* / diagnostic imaging
Spondylitis, Ankylosing* / complications