Trachoma Impact Survey Results from 31 Woredas in Tigray Region, Ethiopia

Ophthalmic Epidemiol. 2024 Dec;31(6):597-604. doi: 10.1080/09286586.2024.2317823. Epub 2024 Dec 27.

Abstract

Purpose: Baseline surveys were conducted in Tigray region, Ethiopia, in 2013. Since then, rounds of azithromycin mass drug administration (MDA) have been delivered in-line with international guidance. The purpose of these surveys was to assess trachomatous inflammation-follicular (TF) prevalence following those treatments to enable the region to plan the next steps towards elimination of trachoma.

Methods: All surveys followed WHO recommendations for community-based cross-sectional survey design. Thirty-one woredas in six zones of Tigray region were surveyed. There were two survey series: all 31 woredas were surveyed in the first series, and 11 woredas were resurveyed in the second, due to having a TF prevalence between 5% and 9.9% in the first series.

Results: In the first series of 31 surveys, one woreda had an adjusted TF prevalence in 1-9-year-olds of <5.0%, 13 had a prevalence of 5.0-9.9% and 17 had a prevalence of 10.0-29.9%. In the second series of 11 surveys, the prevalence of TF was <5.0% in seven woredas and 5.0-9.9% in four woredas. The most recent adjusted prevalence of trachomatous trichiasis (TT) unknown to the health system in ≥15-year-olds was ≥.2% in 27 EUs. One-third of households visited had access to an improved drinking water source within a 30-minute return journey of their house, and 11% had an improved latrine.

Conclusion: Eight woredas met the criteria to stop MDA for 2 years before the re-survey. However, further rounds of MDA, additional efforts to improve water and sanitation access and ongoing strengthening of surgical services for TT are needed across Tigray.

Keywords: Ethiopia; Tigray; neglected tropical disease; trachoma; trachoma impact survey.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents* / therapeutic use
  • Azithromycin / administration & dosage
  • Azithromycin / therapeutic use
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Ethiopia / epidemiology
  • Female
  • Humans
  • Infant
  • Male
  • Mass Drug Administration
  • Middle Aged
  • Prevalence
  • Trachoma* / drug therapy
  • Trachoma* / epidemiology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Azithromycin