Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases

Dietary omega-3 polyunsaturated fatty acids (Dω-3 PUFAs) have been extensively studied and have been proven to offer notable benefits for heart health. Scientific meta-analysis strongly endorses them as potent bioactive agents capable of preventing and managing cardiovascular diseases (CVDs). Fortification of foods with Dω-3 PUFAs is a potential strategy for enhancing Dω-3 PUFA intake in an effort to continue strengthening public health outcomes. This review analyzed recent trends in the fortification of foods with Dω-3 PUFAs in relation to technological developments, challenges linked to the method, and future scope. Additionally, recent clinical trials and research on the effect of Dω-3 PUFA-fortified food consumption on cardiovascular health are reviewed. Technological trends in fortification methods, namely microencapsulation- and nanoencapsulation, have made considerable progress to date, along with excellent stability in both processing and storage conditions and favorable bioaccessibility and sensory attributes of fortified foods. There is a tremendous deal of promise for cardiovascular health based on recent clinical trial findings that fortifying food with Dω-3 PUFAs decreased the incidence of heart disease, blood pressure, and lipid profiles. In summary, substantial progress has been made in addressing the challenges of Dω-3 PUFA fortification. However, further multidisciplinary research is needed to inculcate effectiveness toward achieving the maximum possible Dω-3 PUFAs to protect against the harmful effects of CVDs and continue global health progress.