Screening sites for detection of carbapenemase-producers- a retrospective cohort study

Antimicrob Resist Infect Control. 2024 Dec 31;13(1):157. doi: 10.1186/s13756-024-01513-2.

Abstract

While screening the rectal site and urine may be appropriate for detection of carbapenemase-producing Enterobacterales, respiratory samples, throat and wound swabs may increase the sensitivity of screening protocols when aiming to detect colonization with carbapenemase-producing non-fermenting bacteria. Our results support the need for tailoring screening recommendations according to the bacterial species targeted.

Keywords: Carbapenemase-producing Enterobacterales; Carbapenemase-producing bacteria; Carbapenemases; Non-fermenting bacteria; Screening.

MeSH terms

  • Adult
  • Aged
  • Bacterial Proteins*
  • Enterobacteriaceae / enzymology
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / diagnosis
  • Enterobacteriaceae Infections / microbiology
  • Female
  • Humans
  • Male
  • Mass Screening / methods
  • Middle Aged
  • Pharynx / microbiology
  • Rectum / microbiology
  • Retrospective Studies
  • beta-Lactamases* / metabolism

Substances

  • beta-Lactamases
  • carbapenemase
  • Bacterial Proteins