Two new chromones from Portulaca oleracea L. and their bioactivities

Two new chromones, oleracone H (1) and oleracone I (2), were isolated from Portulaca oleracea L. and identified by UV, IR, UHPLC-ESI-QTOF/MS, 1D NMR, 2D NMR, and CD spectra. In 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, oleracone H (1) and oleracone I (2) presented scavenging activities with IC₅₀ values (half maximal inhibitory concentration) of 16.33 ± 0.20 μM and 22.36 ± 0.41 μM and the abilities of inhibiting the inflammatory factors IL-1β and TNF-α of the two compounds were superior to that of the positive control at 10 μM.