Proximal complement inhibitors in paroxysmal nocturnal hemoglobinuria: an abundance of options in a rare disease

Expert Rev Hematol. 2025 Jan;18(1):5-9. doi: 10.1080/17474086.2025.2449864. Epub 2025 Jan 6.

Authors

Taylor S White¹, Justin R Arnall², Paul Christopher Parish³, Jamie Tolerico³, Thuy Tran², Donald C Moore¹

Affiliations

¹ Department of Pharmacy, Atrium Health, Levine Cancer Institute, Charlotte, NC, USA.
² Department of Pharmacy, Atrium Health Specialty Pharmacy Service, Charlotte, NC, USA.
³ Department of Pharmacy, Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC, USA.

PMID: 39754562
DOI: 10.1080/17474086.2025.2449864

No abstract available

Keywords: Paroxysmal nocturnal hemoglobinuria; complement inhibitor; danicopan; iptacopan; pegcetacoplan.

Publication types

Editorial