A SiO2@Au@Polyaniline (SiO2@Au@PAN) system has been successfully fabricated leveraging the synergistic effects of gold nanoparticles (AuNPs) to realize enhanced photothermal performance. The SiO2@Au@PAN exhibited strong near-infrared (NIR) absorbance, excellent photothermal conversion efficiency, good dispersibility, and outstanding photostability. The SiO2 nanospheres as the template provided numerous binding sites for coating of AuNPs. Subsequently, aniline was grafted onto SiO2 to form PAN, which further facilitated the growth of AuNPs. The high efficiency of electron transfer from PAN to AuNPs was utilized to enhance the photothermal performance, resulting in a photothermal conversion efficiency of 41.47%. Additionally, the effects of SiO2 with different sizes on the anchoring of AuNPs and the impact of aniline with varying concentrations on the morphology and photothermal properties of the materials were investigated. Finally, we verified the photothermal therapeutic (PTT) effect of SiO2@Au@PAN at cellular level, with results demonstrating effective destruction of cancer cells. This work may provide an approach for establishing a multi-component PTT platform based on the synergistic effects of AuNPs, holding significant potential for biomedical and biochemistry applications.
Keywords: Aniline; AuNPs; Near-infrared absorbance; Photothermal conversion; Silica carrier.
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.