Abstract
The anti-PD-1 mAb may be further considered along with PGD2 or active molecules that can promote PGD2 synthesis to enhance the anti-tumor immune response.
Keywords:
Resveratrol; immune checkpoint inhibitors; intestinal microbiota; pancreatic cancer; prostaglandin D2.
MeSH terms
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Animals
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Cell Line, Tumor
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Gastrointestinal Microbiome* / drug effects
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Humans
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Mice
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Programmed Cell Death 1 Receptor* / antagonists & inhibitors
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Programmed Cell Death 1 Receptor* / metabolism
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Prostaglandin D2* / metabolism
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Resveratrol* / pharmacology
Substances
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Resveratrol
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Prostaglandin D2
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Programmed Cell Death 1 Receptor