Complications of Mesenteric Vein Thrombosis: Heterozygous Factor V Leiden Mutation Leads to Pulmonary Embolism in a Patient With Post-Bowel Resection Surgery

Hafiz Muhammad Hamza; Muhammad Muiz Malik; Ayaz Ahmed Awan; Muhammad Daoud Tariq; Mohamed Daoud; Aman Goyal

doi:10.1002/ccr3.70092

Complications of Mesenteric Vein Thrombosis: Heterozygous Factor V Leiden Mutation Leads to Pulmonary Embolism in a Patient With Post-Bowel Resection Surgery

Clin Case Rep. 2025 Jan 6;13(1):e70092. doi: 10.1002/ccr3.70092. eCollection 2025 Jan.

Authors

Hafiz Muhammad Hamza¹, Muhammad Muiz Malik¹, Ayaz Ahmed Awan¹, Muhammad Daoud Tariq¹, Mohamed Daoud², Aman Goyal³

Affiliations

¹ Department of Internal Medicine Foundation University Medical College Islamabad Pakistan.
² Department of Internal Medicine Bogomolets National Medical University Kyiv Ukraine.
³ Department of Internal Medicine Seth GS Medical College and KEM Hospital Mumbai India.

Abstract

It is critical to recognize pulmonary embolism as soon as possible in patients who have gastrointestinal problems pre- and post-surgery. Even in the absence of conventional risk factors, the Factor V Leiden mutation emphasizes the importance of a thorough thrombophilia assessment. To effectively manage and prevent thrombotic episodes, prompt anticoagulant medication and genetic screening for family members are essential.

Keywords: Leiden mutation; bowel resection; factor V; mesenteric vein; pulmonary embolism.