Advances in Exercise and Dietary Interventions for Peripheral Arterial Disease

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2024 Dec;46(6):932-939. doi: 10.3881/j.issn.1000-503X.15928.

Abstract

Peripheral arterial disease(PAD)is a common atherosclerotic cardiovascular disease.The patients with this disease experience pain during exercise,which is relieved after rest.Exercise interventions,dietary interventions,and combined interventions can treat PAD via different mechanisms.Aerobic exercise,resistance exercise,and combined exercise can increase muscle strength and improve cardiorespiratory fitness to regulate vascular endothelial adhesion.Dietary interventions,such as dietary fibre,polyunsaturated fatty acids,and antioxidants,can affect plaque formation via anti-inflammatory and antioxidant mechanisms.The combined exercise and dietary interventions can have synergistic effects.This article reviews the relationship between the two interventions and PAD and describes the current status of research on different interventions,providing a scientific basis for the prevention and treatment of PAD.

外周动脉疾病是一种常见的动脉粥样硬化性心血管病,主要表现为运动时疼痛,休息后缓解。运动干预、饮食干预以及两者联合干预可以通过不同机制对外周动脉疾病产生影响,有氧运动、抗阻运动、联合运动可以通过增加肌肉力量、心肺功能等途径改善血管内皮黏附性,膳食纤维、多不饱和脂肪酸、抗氧化剂等饮食干预通过抗炎、抗氧化等机制影响斑块的形成,运动与饮食联合干预可产生协同作用。本文主要综述运动与饮食两种干预措施与外周动脉疾病之间的关系,阐述不同干预方式的研究现况,为外周动脉疾病防治提供科学依据。.

Keywords: exercise intervention; nutritional intervention; peripheral arterial disease.

Publication types

  • Review

MeSH terms

  • Diet
  • Exercise / physiology
  • Exercise Therapy* / methods
  • Humans
  • Peripheral Arterial Disease* / diet therapy
  • Peripheral Arterial Disease* / therapy