"Motion Capture Suit Sign" for Immunotherapy-Induced Inflammatory Arthritis on 99mTc-MDP Bone Scintigraphy

Clin Nucl Med. 2025 Feb 1;50(2):179-180. doi: 10.1097/RLU.0000000000005591. Epub 2024 Nov 26.

Abstract

We report the 99mTc-MDP bone scan of a 44-year-old man with a history of lung adenocarcinoma and recent multiple joint pain after completing pembrolizumab immunotherapy treatment. This interesting image of symmetric uptakes around bilateral joints throughout the skeleton resembles the ball sensors on a motion capture suit. Hence, we recommend naming this distinctive imaging appearance as the "motion capture suit" sign.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arthritis* / chemically induced
  • Arthritis* / diagnostic imaging
  • Bone and Bones / diagnostic imaging
  • Humans
  • Immunotherapy* / adverse effects
  • Male
  • Motion Capture
  • Radionuclide Imaging*
  • Technetium Tc 99m Medronate*

Substances

  • Technetium Tc 99m Medronate