Analysis of delayed cerebral ischemia incidence after treatment for aneurysmal subarachnoid hemorrhage in young adults: A cohort study

Willian Pegoraro Kus; Felipe Pereira Furtado; Yasmin de França; Roberta Camatti; João Pedro Einsfeld Britz; Vanio Do Livramento Junior Antunes; Luciane Kopittke; Paulo Valdeci Worm

doi:10.25259/SNI_648_2024

Analysis of delayed cerebral ischemia incidence after treatment for aneurysmal subarachnoid hemorrhage in young adults: A cohort study

Surg Neurol Int. 2024 Dec 6:15:449. doi: 10.25259/SNI_648_2024. eCollection 2024.

Authors

Willian Pegoraro Kus¹, Felipe Pereira Furtado², Yasmin de França², Roberta Camatti², João Pedro Einsfeld Britz¹, Vanio Do Livramento Junior Antunes³, Luciane Kopittke⁴, Paulo Valdeci Worm¹

Affiliations

¹ Department of Neurosurgery, Christ the Redeemer Hospital, Porto Alegre, Rio Grande do Sul, Brazil.
² Department of Health Sciences, Medical School, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
³ Department of Medicine, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
⁴ Department of Health Sciences, Conceição Hospital Group, Porto Alegre, Rio Grande do Sul, Brazil.

Abstract

Background: This study aimed to analyze the incidence of delayed cerebral ischemia (DCI) and outcome stratified by age in patients who suffered aneurysmal subarachnoid hemorrhage.

Methods: A cohort study with patients from Christ the Redeemer Hospital from 2014 to 2020, with 359 patients separated into 2 groups, 48 of them aged under 40 years and 311 aged 40 years or over.

Results: In patients under 40 years of age, DCI was found in 81.3%, while in patients aged 40 or over, it was 61.4%. A relative risk of 1.32 (confidence interval: 1.12-1.55), with P = 0.013. After multivariate assessment, patients aged under 40 years were found to have a 27-39% higher risk of presenting DCI.

Conclusion: We identified that age under 40 years is a risk factor for the occurrence of DCI.

Keywords: Cerebral ischemia; Intracerebral aneurysm; Intracranial vasospasm; Subarachnoid hemorrhage.

Publication types

Review