Adult Embryonal Rhabdomyosarcoma of the Prostate Presented on 18F-FDG and Al18F-FAPI-74 PET/CT

Xin Cheng; Guozhu Hou; Rong Zheng; Xi Chen; Xuejuan Wang

doi:10.1097/RLU.0000000000005599

Adult Embryonal Rhabdomyosarcoma of the Prostate Presented on 18F-FDG and Al18F-FAPI-74 PET/CT

Clin Nucl Med. 2024 Dec 30. doi: 10.1097/RLU.0000000000005599. Online ahead of print.

Authors

Xin Cheng¹, Guozhu Hou¹, Rong Zheng¹, Xi Chen², Xuejuan Wang¹

Affiliations

¹ From the Department of Nuclear Medicine (PET-CT Center), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
² Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

PMID: 39787402
DOI: 10.1097/RLU.0000000000005599

Abstract

A 21-year-old man with a 2-week history of abdominal pain and urinary hesitancy was admitted to our hospital. Sarcoma was suspected based on his PSA level, age, and MRI findings. He underwent 18F-FDG and Al18F-FAPI-74 PET/CT scans. The scans revealed an irregularly dense prostate mass with indistinct borders to the rectum. The mass exhibited increased and heterogeneous FDG uptake and FAPI activity, with different distribution patterns between the 2 tracers. Histopathological analysis confirmed the diagnosis of embryonal rhabdomyosarcoma.