Spiro-Ometad As A Promising Substrate In Biomedical Devices

Lisa Titze; Francesca Cadamuro; Nicoletta Murenu; Raziyeh Akbari; Luca Pellegrino; Giancarlo Capitani; Maurizio Acciarri; Carlo Antonini; Laura Russo; Norberto Manfredi

doi:10.1002/open.202400002

Spiro-Ometad As A Promising Substrate In Biomedical Devices

ChemistryOpen. 2025 Jan 10:e202400002. doi: 10.1002/open.202400002. Online ahead of print.

Affiliations

¹ Department of Materials Science and Milano-Bicocca Solar Energy Research Center - MIB-Solar, University of Milano-Bicocca, Via Cozzi 55, Milano, I-20125, Italy.
² School of Medicine and Surgery, University of Milano-Bicocca, Via Raoul Follereau 3, Vedano al Lambro (MB), I-20854, Italy.
³ Department of Earth and Environmental Sciences, University of Milano-Bicocca, Piazza della Scienza 1, Milano, I-20126, Italy.

PMID: 39790026
DOI: 10.1002/open.202400002

Abstract

Bioactive films composed of Spiro-OMeTAD, a conductive molecular material (CMM), in combination with collagen have been manufactured and characterised for the first time. In-vitro cellular testing demonstrated the non-cytotoxicity of the doped Spiro-OMeTAD /Collagen films, opening the way for implantable or wearable medical devices and biosensors based on molecular materials.

Keywords: Biosensors; Collagen; Conductivity; Cytotoxicity; Spiro-OMeTAD.