Unconventional Imaging Methods in Psoriatic Arthritis

Curr Rheumatol Rep. 2025 Jan 10;27(1):13. doi: 10.1007/s11926-024-01174-5.

Abstract

Purpose of review: Psoriatic arthritis (PsA) is a complex heterogeneous inflammatory disease that affects about one-third of patients with psoriasis. PsA leads to significant physical impairment and reduced quality of life. Therefore, early diagnosis and intervention are critical for improving long-term outcomes. The purpose of this review is to highlight the advantages of unconventional imaging methods in the diagnosis and management of PsA and to discuss recent advancements in imaging technology.

Recent findings: Conventional imaging methods, such as radiography, musculoskeletal ultrasound, and magnetic resonance imaging, have been instrumental in detecting structural joint damage and inflammation. However, these imaging modalities have several limitations, resulting in their inability to detect early disease changes. Recent advancements in imaging technology have led to the development of novel imaging modalities capable of characterizing not only early structural but also molecular aspects of disease activity. These cutting-edge approaches have been lately applied to both psoriasis and PsA patients, offering new insights into disease progression, the transition from psoriasis to PsA, and treatment responses. By providing more detailed and individualized assessments, unconventional imaging modalities may bring us closer to realizing the potential of personalized medicine in the management of PsA.

Keywords: Artificial intelligence; Metabolic imaging; Optoacoustic imaging; Positron emission tomography; Psoriatic arthritis.

Publication types

  • Review

MeSH terms

  • Arthritis, Psoriatic* / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging* / methods
  • Ultrasonography / methods