Psychedelic Medicine Exceptionalism

Am J Bioeth. 2025 Jan;25(1):6-15. doi: 10.1080/15265161.2025.2434398. Epub 2025 Jan 13.

Abstract

Research on psychedelic medicines is experiencing a revival. Some clinicians, scientists, and ethicists believe that psychedelics are so different from other treatments that they warrant special consideration in how they are researched, regulated, commercialized, and administered. Others argue that psychedelic medicines show clinical potential, but they should be treated like other medical interventions. In other words, identical standards should apply. This article analyzes whether psychedelic medicines warrant special consideration from a regulatory and ethical perspective.

Keywords: FDA; MDMA; Psychedelics; informed consent; psilocybin; psychotherapy.

MeSH terms

  • Hallucinogens* / administration & dosage
  • Hallucinogens* / adverse effects
  • Hallucinogens* / therapeutic use
  • Humans
  • United States

Substances

  • Hallucinogens