The Novel HLA-DPB1*1498:01 Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

HLA. 2025 Jan;105(1):e70018. doi: 10.1111/tan.70018.

Authors

Can Lou^{1

2}, Zhi-Cong Xie³, Li Ma³, Xiao-Zhuang Hu³, Hang Lei^{1

2}

Affiliations

¹ Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Blood Transfusion Department, Ruijin Hospital, Medical School of Shanghai Jiao Tong University, Shanghai, China.
³ Department of Laboratory, Shanghai Tissuebank Biotechnology Co. Ltd, Shanghai, China.

PMID: 39807670
DOI: 10.1111/tan.70018

Abstract

The HLA-DPB1*1498:01 allele differs from HLA-DPB1*02:02:01:01 by a single non-synonymous nucleotide change in exon 4.

Keywords: HLA‐DPB1*1498:01; novel allele; sequencing‐based typing.

© 2025 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Letter

MeSH terms

Alleles*
Asian People* / genetics
Base Sequence*
Codon
East Asian People
Exons*
HLA-DP beta-Chains* / genetics
Histocompatibility Testing*
Humans
Polymorphism, Single Nucleotide
Sequence Alignment
Sequence Analysis, DNA* / methods
Tissue Donors

Substances

HLA-DP beta-Chains
HLA-DPB1 antigen
Codon