A Highly Selective Probe for Real-Time Monitoring of Ethylenediamine with Ratiometric Luminescent and Colorimetric Dual-Mode Responses

Qian Zhou; Xiurong Ma; Xian Meng; Runying He; Caihong Shi; Yonggang Shi; Qiue Cao; Liyan Zheng

doi:10.1021/acs.analchem.4c04080

A Highly Selective Probe for Real-Time Monitoring of Ethylenediamine with Ratiometric Luminescent and Colorimetric Dual-Mode Responses

Anal Chem. 2025 Jan 14. doi: 10.1021/acs.analchem.4c04080. Online ahead of print.

Authors

Qian Zhou¹, Xiurong Ma¹, Xian Meng¹, Runying He¹, Caihong Shi¹, Yonggang Shi¹, Qiue Cao¹, Liyan Zheng¹

Affiliation

¹ Key Laboratory of Medicinal Chemistry for Natural Resource of Yunnan, University Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, P. R. China.

PMID: 39807755
DOI: 10.1021/acs.analchem.4c04080

Abstract

Ethylenediamine (EDA), as an important chemical raw material and fine chemical intermediate, has been widely applied in various industries. Real-time monitoring of EDA is highly desirable in daily life due to its potential threat to human health. Herein, we report a molecular probe named 4,4'-(9H-carbazole-3,6-diyl)bis(1-(naphthalen-2-ylmethyl)pyridin-1-ium) iodide (p-N-DPC·I₂) with ratiometric luminescent and colorimetric dual-mode responses toward EDA, endowing a highly sensitive and selective detection method for its real-time monitoring. The experimental and theoretical calculation results revealed that the response mechanism was due to forming a charge transfer (CT) state when p-N-DPC·I₂ met with EDA. In addition, a hydrogel-based sensing chip was developed to achieve the ultrasensitive recognition of EDA vapor with the naked eye at a concentration as low as 10 ppm. This study developed a new probe with ratiometric fluorescent and colorimetric modes to detect EDA both in solution and vapor.