Photoinduced Azidoamination of Styrenes Using Sodium Azide and (Diphenylmethylene)amino Benziodoxolone

Kensuke Kiyokawa; Koki Nakano; Daichi Okumatsu; Satoshi Minakata

doi:10.1002/asia.202401493

Photoinduced Azidoamination of Styrenes Using Sodium Azide and (Diphenylmethylene)amino Benziodoxolone

Chem Asian J. 2025 Jan 14:e202401493. doi: 10.1002/asia.202401493. Online ahead of print.

Authors

Kensuke Kiyokawa¹, Koki Nakano¹, Daichi Okumatsu¹, Satoshi Minakata²

Affiliations

¹ Osaka University: Osaka Daigaku, Department of Applied Chemistry, JAPAN.
² Osaka University, Department of Applied Chemistry, Yamadaoka 2-1, 565-0871, Suita, JAPAN.

PMID: 39809706
DOI: 10.1002/asia.202401493

Abstract

Herein, we report the radical azidoamination of styrenes via the use of a combination of sodium azide and (diphenylmethylene)amino benziodoxolone under visible-light irradiation. This approach to unsymmetrical diamination provides a simple and practical method for constructing vicinal diamine scaffolds with two distinct and easily modifiable amino functionalities.

Keywords: amination; azide; iodine; radical; synthetic methods.