Eruptive Pseudoangiomatosis in Adults: A Case Report of an Unfamiliar Association With Neurological Symptoms

Cureus. 2024 Dec 15;16(12):e75747. doi: 10.7759/cureus.75747. eCollection 2024 Dec.

Abstract

Eruptive pseudoangiomatosis (EP) is a rare cutaneous condition that usually resolves spontaneously within a few days and is more frequently seen in the pediatric age group. It is characterized by the sudden onset of asymptomatic small erythematous hemangioma-like papules encircled by a pale halo. The precise pathogenesis is unknown; however, multiple environmental triggers have been reported. This case report aims to highlight the complex presentation of EP with concurrent neurological symptoms in an adult patient. Herein, we report a 26-year-old male, not known to have any medical illnesses, admitted to our hospital as a case of a motor vehicle accident due to a syncopal attack while driving. Multiple previous syncopal attacks passed unnoticeably in the previous couple of months without being investigated. During admission, dermatology was consulted for an abrupt onset of small discrete asymptomatic, bright red well-delimited macules and papules, measuring 2-3 mm in diameter, surrounded by a pale halo located on the distal upper and lower extremities with the involvement of palms and soles. Neurological evaluation revealed bilateral lower limb weakness and sensory deficits. A skin biopsy was non-specific due to delayed sampling. Syphilis serologies and other labs were unremarkable. The patient has been investigated by neurology and is currently on an implantable loop recorder. This case underscores the importance of considering EP in the differential diagnosis of abrupt dermatological eruptions, particularly when accompanied by neurological symptoms, warranting further investigation into potential underlying conditions.

Keywords: adult; case report; eruptive pseudoangiomatosis; neurology; syncope.

Publication types

  • Case Reports