Prevalence and Mitigation of Cardiovascular Disease Risk Factors Among the Corporate Workforce in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

Cardiovascular disease (CVDs) is the leading cause of mortality worldwide. Corporate workplaces have been identified as important environmental factors that can increase the risk and severity of CVDs. Evidence indicates that the risk and severity of CVDs can be effectively reduced by mitigating modifiable behavioural and intermediate risk factors. Although the prevalence of CVDs and their associated risk factors is increasing in sub-Saharan Africa (SSA), most published data from the region are hospital-based and may not be true estimates. This study investigated the prevalence and distribution of CVD risk factors among the corporate workforce in SSA and the effects of workplace wellness programmes (WWP) on these risk factors. Accordingly, a systematic search was performed using Google Scholar, Cochrane Library, PubMed, MEDLINE, Scopus and Science Direct for articles published between January 2010 and March 2024. A total of 105 studies (n = 76,027) across nine countries met the eligibility criteria and were analysed. The pooled prevalence of the risk factors was unhealthy diet (80%), high salt intake (32%), stress (58%), poor sleep (59%), physical inactivity (PI, 59%), alcohol consumption (29%), harmful alcohol consumption (26%), tobacco smoking (7%), khat chewing (6%), overweight (36%), obesity (23%), central obesity (44%), high blood pressure (29%), high total cholesterol (33%), high low-density lipoprotein cholesterol (LDL-c) (41%), low high-density lipoprotein cholesterol (HDL-c) (45%), hypertriglyceridaemia (17%), dysglycaemia (9%), and metabolic syndrome (MS; 45%). The highest prevalence of unhealthy diet and PI was recorded in East Africa and Central Africa, respectively, whereas West Africa had the highest prevalence of high body mass index (BMI). Ethiopia had the highest prevalence of unhealthy diets, whereas Nigeria had the highest prevalence of stress and poor sleep. The healthcare sector had the highest cluster of risk factors and the highest prevalence of unhealthy diets. Only 5.7% of the studies implemented WWP, which had significant mitigating effects on most risk factors. This study concluded that the prevalence of most modifiable CVD risk factors is high among the corporate workforce in SSA, which is higher than that in the general population in most cases, and a well-designed WWP can significantly mitigate these risk factors.