Suspected Transient Ischemic Attack Related to Dysfunctional Quadricuspid Aortic Valve

J Investig Med High Impact Case Rep. 2025 Jan-Dec:13:23247096251313625. doi: 10.1177/23247096251313625.

Abstract

We describe a 30-year-old Caribbean-Black woman with a clinical presentation suggestive of a transient ischemic attack (TIA) with no conventional cerebrovascular risk factors, albeit with a newly diagnosed quadricuspid aortic valve (QAV) with moderate aortic regurgitation (AR). Although QAV is a recognized congenital cardiac defect, its association with TIA remains elusive. This case highlights the importance of considering potential atypical etiologies, such as QAV, in the evaluation and management of young patients presenting with cerebrovascular events.

Keywords: aortic regurgitation; quadricuspid aortic valve; transient ischemic attack.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aortic Valve Insufficiency* / diagnostic imaging
  • Aortic Valve Insufficiency* / etiology
  • Aortic Valve* / abnormalities
  • Aortic Valve* / diagnostic imaging
  • Echocardiography
  • Echocardiography, Transesophageal
  • Female
  • Heart Defects, Congenital / complications
  • Heart Defects, Congenital / diagnostic imaging
  • Humans
  • Ischemic Attack, Transient* / etiology