Adult Kerion Caused by Trichophyton tonsurans

Mycopathologia. 2025 Jan 22;190(1):17. doi: 10.1007/s11046-024-00911-9.

Abstract

Adult tinea capitis, especially kerion, caused by Trichophyton tonsurans is relatively rare in China. Here, we report a case caused by the agent in an old woman with normal immune function. Fungal microscopic examination and culture were positive. The isolate was further identified as Trichophyton tonsurans by internal transcribed spacer (ITS) sequencing. Skin biopsy and histopathological examination suggested diffuse inflammatory cell infiltration in the dermis and subcutaneous tissue. Notably, fungal spores were observed within the dermis by Periodic acid-Schiff (PAS) staining. After eight weeks of treatment with oral griseofulvin and topical luliconazole, the patient's abscess subsided, hair regrowth occurred without scarring, and the mycologic examination returned negative.

Keywords: Trichophyton tonsurans; Adult tinea capitis; Kerion.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Aged
  • Antifungal Agents* / therapeutic use
  • Arthrodermataceae / classification
  • Arthrodermataceae / genetics
  • Arthrodermataceae / isolation & purification
  • Biopsy
  • China
  • DNA, Fungal / genetics
  • DNA, Ribosomal Spacer / chemistry
  • DNA, Ribosomal Spacer / genetics
  • Female
  • Griseofulvin / administration & dosage
  • Griseofulvin / therapeutic use
  • Histocytochemistry
  • Humans
  • Imidazoles
  • Microbiological Techniques
  • Microscopy
  • Middle Aged
  • Sequence Analysis, DNA
  • Skin / microbiology
  • Skin / pathology
  • Tinea Capitis* / diagnosis
  • Tinea Capitis* / drug therapy
  • Tinea Capitis* / microbiology
  • Tinea Capitis* / pathology
  • Treatment Outcome

Substances

  • Antifungal Agents
  • DNA, Ribosomal Spacer
  • Griseofulvin
  • luliconazole
  • DNA, Fungal
  • Imidazoles

Supplementary concepts

  • Trichophyton tonsurans