Therapeutic Bioactivities and Chemical Composition Analysis of Rhizome Oleoresin of Hedychium coronarium Collected from Uttarakhand, India

Sushila Arya; Ravendra Kumar; Om Prakash; Mamta Latwal; Ganesh Pandey; Satya Kumar; R M Srivastava; Suraj N Mali

doi:10.2174/0113862073327439241119113953

Therapeutic Bioactivities and Chemical Composition Analysis of Rhizome Oleoresin of Hedychium coronarium Collected from Uttarakhand, India

Comb Chem High Throughput Screen. 2025 Jan 7. doi: 10.2174/0113862073327439241119113953. Online ahead of print.

Authors

Sushila Arya^{1

2}, Ravendra Kumar¹, Om Prakash¹, Mamta Latwal³, Ganesh Pandey², Satya Kumar⁴, R M Srivastava⁵, Suraj N Mali⁶

Affiliations

¹ Department of Chemistry, College of Basic Science and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, India.
² Department of Agriculture, Dev Bhoomi Uttarakhand University, Dehradun, Uttarakhand, India.
³ Department of Chemistry, School of Engineering, University of Petroleum and Energy Studies (UPES), Bidholi campus, Dehradun, Uttarakhand, India.
⁴ Department of Plant Pathology, College of Agriculture, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, India.
⁵ Department of Entomology, College of Agriculture, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, India.
⁶ School of Pharmacy, D.Y. Patil University (Deemed to be University), Sector 7, Nerul, Navi Mumbai 400706, India.

PMID: 39843450
DOI: 10.2174/0113862073327439241119113953

Abstract

Introduction: Hedychium coronarium J. König, from the Zingiberaceae family, is a rhizomatous herb used in Ayurvedic medicine for its febrifuge, anti-rheumatic, and anthelmintic properties.

Method: This study characterizes the chemical diversity and biological activities of H. coronarium oleoresins collected from four locations in Uttarakhand: Pantnagar (HCPNOR), Bageshwar (HCBOR), Nainital (HCNOR) and Pithoragarh (HCPOR). GC-MS analysis identified key constituents, including n-Hexadecanoic acid (8.3-9.8%), photocitral B (4.8- 27.6%), (Z)-9- eicosenoic acid (0.7-6.5%), α-pinene (2.5-3.5%) and trans-13-octadecenoic acid (7.5%). Heat map clustering, Venn diagrams, and PCA revealed compositional variations.

Result: The oleoresins showed potent nematicidal, insecticidal, herbicidal, and antifungal activities against Meloidogyne incognita, Spodoptera litura, Raphanus raphanistrum subsp. sativus, Fusarium oxysporum, and Curvularia lunata.

Conclusion: These findings highlight the potential of H. coronarium oleoresins for pest and pathogen management, with chemical variation driven by environmental factors.

Keywords: Hedychium coronarium; biological activities.; oleoresins; α-pinene.