A 54-year-old man presented with a 1-month history of pain and numbness in the right lower limb. Lumbar spine MRI revealed bone metastases. 18F-FDG PET/CT showed a soft tissue mass with increased 18F-FDG uptake in the rectum, accompanied by multiple hypermetabolic lesions in the bilateral ribs, spine, pelvis, and upper right femur. A colonoscopy biopsy of the submucosal rectal mass confirmed the diagnosis of epithelioid angiosarcoma.
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