Spatial distribution of immune cells and their proximity to STING+ cells are associated with survival in glioblastoma

Spatial distribution of immune cells and their proximity to STING⁺ cells are associated with survival in glioblastoma

Clin Transl Med. 2025 Feb;15(2):e70187. doi: 10.1002/ctm2.70187.

Hanwool Jeon^{1

2

3}, Hayeong Kang^{1

2

3}, Jihyun Im^{1

2

3}, Suin Jo⁴, Hyunchul Jung¹, Moinay Kim¹, Jae Hyun Kim⁵, Eunyeup Lee^{1

2

3}, Soyoung Kim^{1

2

3}, Jeong Hoon Kim¹, Chang-Ki Hong¹, Young-Hoon Kim¹, Sang Woo Song¹, Jinha Park⁴, Sang-Yeob Kim⁶, Seungjoo Lee^{1

2

3}

¹ Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
² Translational Biomedical Research Group, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.
³ Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Seoul, Republic of Korea.
⁴ PrismCDX Co., Ltd., Hwaseong-si, Hwaseong, Republic of Korea.
⁵ Department of Neurosurgery, Dongsan Medical Center, Keimyung University College of Medicine, Daegu, Republic of Korea.
⁶ Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.

No abstract available

Keywords: glioblastoma; multiplex IHC; spatial analysis; tumour immune microenvironment.