Reactive oxygen dependent activation of polycyclic hydrocarbons by phorbol ester-stimulated human polymorphonuclear leukocytes

Carcinog Compr Surv. 1985:8:293-303.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Benzopyrenes / metabolism
  • Biotransformation
  • Carcinogens / metabolism*
  • DNA / metabolism
  • Dihydroxydihydrobenzopyrenes*
  • Humans
  • Luminescent Measurements
  • Lung Neoplasms / chemically induced
  • Mutagenicity Tests
  • Neutrophils / drug effects
  • Neutrophils / metabolism*
  • Oxidation-Reduction
  • Oxygen / metabolism*
  • Phorbols / pharmacology*
  • Polycyclic Compounds / metabolism*
  • Superoxide Dismutase / pharmacology
  • Tetradecanoylphorbol Acetate / pharmacology*

Substances

  • Benzopyrenes
  • Carcinogens
  • Dihydroxydihydrobenzopyrenes
  • Phorbols
  • Polycyclic Compounds
  • benzo(a)pyrene 7,8-dihydrodiol
  • DNA
  • Superoxide Dismutase
  • Tetradecanoylphorbol Acetate
  • Oxygen