Protein kinase stimulated by cyclic GMP in uninfected and simian virus 40-infected monkey kidney cells

J Virol. 1974 Jan;13(1):234-6. doi: 10.1128/JVI.13.1.234-236.1974.

Abstract

Uninfected African green monkey kidney cells contain a cyclic GMP-stimulated protein kinase. The level or specific activity of the enzyme was not significantly increased after infection of the cells with simian virus 40. This enzyme probably catalyzes the phosphorylation of the structural proteins of the virus.

Publication types

  • Comparative Study

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Animals
  • Cell Line
  • Cell Nucleus / enzymology
  • Cell-Free System
  • Cells, Cultured / enzymology*
  • Centrifugation, Density Gradient
  • Chemical Precipitation
  • Chromatography, DEAE-Cellulose
  • Cyclic AMP / pharmacology
  • Cyclic GMP / pharmacology*
  • Cytoplasm / enzymology
  • Haplorhini
  • Kidney
  • Magnesium / pharmacology
  • Protein Kinases / isolation & purification
  • Protein Kinases / metabolism*
  • Simian virus 40 / growth & development*
  • Tritium

Substances

  • Tritium
  • Adenosine Triphosphate
  • Cyclic AMP
  • Protein Kinases
  • Cyclic GMP
  • Magnesium