Relationship between antihistamine and antidepressant activity in hexahydroindenopyridines

J Med Chem. 1972 May;15(5):466-70. doi: 10.1021/jm00275a006.
No abstract available

MeSH terms

  • Amphetamine / pharmacology
  • Animals
  • Antidepressive Agents / chemical synthesis*
  • Antidepressive Agents / pharmacology
  • Blood Pressure / drug effects
  • Body Temperature / drug effects
  • Cats
  • Dogs
  • Drug Antagonism
  • Drug Synergism
  • Histamine H1 Antagonists / chemical synthesis*
  • Histamine H1 Antagonists / pharmacology
  • Indenes / chemical synthesis*
  • Indenes / pharmacology
  • Male
  • Mice
  • Models, Structural
  • Norepinephrine / pharmacology
  • Pyridines / chemical synthesis*
  • Pyridines / pharmacology
  • Rats
  • Reserpine / antagonists & inhibitors
  • Stereoisomerism
  • Structure-Activity Relationship
  • Tetrabenazine / antagonists & inhibitors

Substances

  • Antidepressive Agents
  • Histamine H1 Antagonists
  • Indenes
  • Pyridines
  • Reserpine
  • Amphetamine
  • Norepinephrine
  • Tetrabenazine