Suppression of puerperal lactation with an ergot alkaloid: a double-blind study

Br Med J. 1972 Jun 24;2(5816):743-4. doi: 10.1136/bmj.2.5816.743.

Abstract

A double-blind trial was performed in 60 women to establish the effectiveness of an ergot alkaloid, 2-Br-alpha-ergocryptine (ergocryptine; CB 154), in suppressing puerperal lactation and to compare it with stilboestrol and a placebo. At the doses selected ergocryptine and stilboestrol were equally effective.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Breast / drug effects
  • Clinical Trials as Topic
  • Diethylstilbestrol / administration & dosage
  • Diethylstilbestrol / pharmacology
  • Dosage Forms
  • Ergot Alkaloids / administration & dosage
  • Ergot Alkaloids / pharmacology*
  • Female
  • Follow-Up Studies
  • Humans
  • Lactation / drug effects*
  • Placebos
  • Postpartum Period*
  • Pregnancy

Substances

  • Dosage Forms
  • Ergot Alkaloids
  • Placebos
  • Diethylstilbestrol