Trisomy 9 mosaicism with multiple congenital anomalies

J Med Genet. 1973 Jun;10(2):180-4. doi: 10.1136/jmg.10.2.180.

Abstract

A nine-year-old male with developmental abnormalities was found to be mosaic for an extra No. 9 chromosome (46,XY/47,XY,+9). The clinical findings included severe mental retardation, peculiar facies, short stature, hypotonia, dextroposition with a ventricular septal defect, and patent ductus arteriosus, as well as significant abnormalities of the brain.

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Adult
  • Child
  • Child, Preschool
  • Chromosome Aberrations
  • Chromosome Disorders
  • Chromosome Mapping
  • Chromosomes, Human, 6-12 and X*
  • Dextrocardia / genetics
  • Female
  • Growth Disorders / genetics
  • Humans
  • Hyperbilirubinemia / genetics
  • Infant
  • Infant, Newborn
  • Intellectual Disability / genetics
  • Karyotyping
  • Male
  • Mosaicism*
  • Pregnancy
  • Pregnancy Complications
  • Trisomy*
  • Uterine Hemorrhage / complications