Toxicity of E. coli L-asparaginase in man

Cancer. 1970 Feb;25(2):253-78. doi: 10.1002/1097-0142(197002)25:2<253::aid-cncr2820250204>3.0.co;2-u.
No abstract available

MeSH terms

  • Adult
  • Agranulocytosis / chemically induced
  • Antigen-Antibody Reactions
  • Asparaginase / administration & dosage
  • Asparaginase / toxicity*
  • Blood Platelet Disorders / chemically induced
  • Bone Marrow / drug effects
  • Calcium / blood
  • Calcium / urine
  • Chemical and Drug Induced Liver Injury
  • Child
  • Cognition Disorders / chemically induced
  • Diarrhea / chemically induced
  • Escherichia coli / enzymology
  • Female
  • Fever / drug therapy
  • Hemorrhage / chemically induced
  • Humans
  • Hypersensitivity, Immediate
  • Injections, Intravenous
  • Leukemia / drug therapy*
  • Lipids / blood
  • Liver Function Tests
  • Lymphoma / drug therapy*
  • Lymphopenia / chemically induced
  • Male
  • Nausea / chemically induced
  • Nitrogen / blood
  • Nitrogen / urine
  • Pancreatitis / chemically induced
  • Phosphorus / urine
  • Time Factors
  • Uric Acid / urine
  • Vomiting / chemically induced

Substances

  • Lipids
  • Uric Acid
  • Phosphorus
  • Asparaginase
  • Nitrogen
  • Calcium