A marsupial oncovirus?

J Gen Virol. 1979 Aug;44(2):535-9. doi: 10.1099/0022-1317-44-2-535.

Abstract

A virus-like particle was observed in two continuous cell lines derived from the marsupial Sminthopsis crassicaudata (Fat-tailed Dunnart). The development of the particle was similar to the development of D-type oncoviruses. Initially, a crescentof nucleoid material was observed near the nucleus in the region of the Golgi apparatus. This crescent developed into a doughnut-shaped-A-type particle which migrated through the cytoplasm towards the cell membrane where it budded either into a smooth membrane cytoplasmic vacuole or from the cell membrane. Only enveloped A-type particles were observed; no mature B-type, C-type or D-type particles were detected.

MeSH terms

  • Animals
  • Cell Line*
  • Cell Membrane / microbiology
  • Cell Membrane / ultrastructure
  • Cytoplasm / microbiology
  • Cytoplasm / ultrastructure
  • Marsupialia*
  • Oncogenic Viruses / classification
  • Oncogenic Viruses / growth & development*
  • Oncogenic Viruses / ultrastructure