Abstract
An infectious clone of the linear, unintegrated RadLV provirus was obtained by insertion in the plasmid pBR322. Its restriction map was indistinguishable from that of the majority of the multiple proviral copies, which are found apparently at random sites in the DNA of RadLV-induced rat thymic lymphomas.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Base Sequence
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Cloning, Molecular*
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DNA Restriction Enzymes
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DNA, Neoplasm / genetics*
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DNA, Neoplasm / isolation & purification
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DNA, Viral / genetics
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DNA, Viral / isolation & purification
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Genes, Viral*
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Leukemia Virus, Murine / genetics*
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Leukemia, Radiation-Induced / genetics
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Leukemia, Radiation-Induced / microbiology*
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Mice
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Mice, Inbred Strains
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Thymus Neoplasms / genetics
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Thymus Neoplasms / microbiology*
Substances
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DNA, Neoplasm
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DNA, Viral
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DNA Restriction Enzymes