Tumorigenicity of a rabbit lymphoid cell line transformed by human T-cell leukemia virus

Gan. 1984 Jun;75(6):482-4.

Abstract

A rabbit lymphoid cell line transformed by human T-cell leukemia virus (HTLV) was inoculated into the peritoneal cavity of six newborn hamsters treated by antilymphocyte serum. All of them developed lethal tumors two weeks after implantation. The tumor cells were chromosomally of rabbit type, and harbored HTLV and HTLV antigens.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Antilymphocyte Serum / pharmacology
  • Cell Line
  • Cell Transformation, Viral*
  • Chromosomes / ultrastructure
  • Cricetinae
  • Deltaretrovirus / pathogenicity*
  • Lymphocytes / microbiology
  • Neoplasm Transplantation
  • Neoplasms, Experimental / etiology*
  • Neoplasms, Experimental / genetics
  • Rabbits

Substances

  • Antilymphocyte Serum