The disposition and metabolism of an orexigenic agent, 10,11-dihydro-5-(1-methyl-4-piperidinylidene)-5H-dibenzo[a,d]cyclohepten-3-carboxylic acid, in the rat, dog, and cat

Drug Metab Dispos. 1981 Sep-Oct;9(5):428-33.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Blood-Brain Barrier
  • Brain / metabolism
  • Carbon Radioisotopes
  • Cats
  • Chromatography, Gas
  • Cyproheptadine / analogs & derivatives*
  • Cyproheptadine / metabolism
  • Dogs
  • Gas Chromatography-Mass Spectrometry
  • Kinetics
  • Male
  • Metabolic Clearance Rate
  • Rats
  • Rats, Inbred Strains
  • Species Specificity
  • Tissue Distribution

Substances

  • Carbon Radioisotopes
  • Cyproheptadine
  • MK 711