Abstract
Antibodies against human prealbumin (HPA) give a strong immunoperoxidase staining of the A (glucagon) pancreatic cells and of glucagon-, insulin- and gastrin-producing pancreatic tumours. The majority of intestinal and bronchial carcinoids are also reactive. The staining may be related to presence in the C-terminal sequence of HPA of determinants in common with polypeptide (pro-) hormones.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenoma, Islet Cell / analysis*
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Binding Sites, Antibody / analysis*
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Bronchial Neoplasms / analysis*
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Carcinoid Tumor / analysis*
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Carcinoma / analysis
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Glucagonoma / analysis
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Histocytochemistry
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Humans
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Immunoenzyme Techniques
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Insulinoma / analysis
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Intestinal Neoplasms / analysis*
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Pancreatic Neoplasms / analysis*
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Prealbumin / immunology*
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Zollinger-Ellison Syndrome / analysis