Betaxolol and propranolol in glucagon stimulation of growth hormone

Arch Dis Child. 1984 Jul;59(7):670-2. doi: 10.1136/adc.59.7.670.

Abstract

Both betaxolol and propranolol, beta blockers with different pharmacological properties, increase the reliability of somatotropic testing with glucagon. The combination of glucagon and betaxolol, however, is much better tolerated than that of glucagon and propranolol. The use of a beta 1 cardioselective adrenoceptor block for growth hormone testing is recommended.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adrenergic beta-Antagonists*
  • Betaxolol
  • Child
  • Child, Preschool
  • Female
  • Glucagon*
  • Growth Disorders / physiopathology
  • Growth Hormone / metabolism*
  • Humans
  • Infant
  • Male
  • Propanolamines*
  • Propranolol*
  • Stimulation, Chemical

Substances

  • Adrenergic beta-Antagonists
  • Propanolamines
  • Growth Hormone
  • Glucagon
  • Propranolol
  • Betaxolol