If the shoulder-hand syndrome is left without special care, it may lead to severe painful disabilities of the upper extremity. Early recognition of the clinical signs and symptoms and aggressive total care are essential for successful treatment and for the prevention of severe flexion contractures of the hand and shoulder, especially in patients whose symptoms have developed after a cerebrovascular accident. An outline is given of the treatment modalities (corticosteroids, physiotherapy and mechanical devices) used at the Institute for Rehabilitation Medicine (NYU) for obtaining maximum function of the involved upper extremity.