Haemoglobin O Arab, beta-thalassaemia and glucose-6-phosphate dehydrogenase deficiency in a Hungarian family

M Horányi; J Szelényi; G Rona; A Lang; H Lehmann; S R Hollán

Haemoglobin O Arab, beta-thalassaemia and glucose-6-phosphate dehydrogenase deficiency in a Hungarian family

Folia Haematol Int Mag Klin Morphol Blutforsch. 1980;107(4):654-60.

Authors

M Horányi, J Szelényi, G Rona, A Lang, H Lehmann, S R Hollán

PMID: 6162733

Abstract

A 29-year-old Hungarian woman was found to be double heterozygote for Hb O Arab and beta-thalassaemia. Haemolytic anaemia became manifest during her second pregnancy. In the course of genetic studies G-6-PD deficiency was also detected in the family. The patient originates from a North-Eastern part of Hungary which had been hydrogeologically isolated during past centuries.

Publication types

Case Reports

MeSH terms

Adult
Anemia, Hemolytic / complications*
Anemia, Hemolytic / genetics
Female
Glucosephosphate Dehydrogenase Deficiency / complications*
Glucosephosphate Dehydrogenase Deficiency / genetics
Hemoglobins, Abnormal* / analysis
Heterozygote
Humans
Hungary
Pedigree
Pregnancy
Pregnancy Complications, Hematologic* / genetics
Thalassemia / complications*
Thalassemia / genetics

Substances

Hemoglobins, Abnormal