Abstract
Whole blood and plasma histamine levels, peripheral basophil and eosinophil counts and serum immunoglobulins have been measured in a group of eighteen patients with migraine in remission and in twelve of these patients during a headache attack. Plasma histamine levels were significantly elevated (P less than 0.0005) in patients with migraine both during headache attacks and symptom-free periods.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Basophils
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Eosinophils
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Female
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Histamine / blood*
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Histamine Release
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Humans
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Immunoglobulin A / biosynthesis
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Immunoglobulin E / biosynthesis
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Leukocyte Count
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Male
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Mast Cells / metabolism
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Middle Aged
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Migraine Disorders / blood*
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Migraine Disorders / complications
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Migraine Disorders / immunology
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Rhinitis, Allergic, Seasonal / complications
Substances
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Immunoglobulin A
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Immunoglobulin E
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Histamine