Phase I study of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (NSC 95466) in adults with solid tumors

Cancer Res. 1980 Oct;40(10):3750-4.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Agranulocytosis / chemically induced
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / pathology
  • Drug Administration Schedule
  • Drug Evaluation
  • Female
  • Glioblastoma / drug therapy
  • Glioblastoma / pathology
  • Glioma / drug therapy
  • Glioma / pathology
  • Humans
  • Hypotension / chemically induced
  • Male
  • Middle Aged
  • Mustard Compounds / administration & dosage
  • Mustard Compounds / adverse effects
  • Nausea / chemically induced
  • Neoplasms / drug therapy*
  • Neoplasms / pathology
  • Nitrosourea Compounds / administration & dosage*
  • Nitrosourea Compounds / adverse effects
  • Thrombocytopenia / chemically induced

Substances

  • Mustard Compounds
  • Nitrosourea Compounds
  • 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea