Abstract
Four cases are presented in which children receiving radiation therapy and combination chemotherapy had unilateral severe and prolonged neurotoxic effects. Augmentation of vincristine neurotoxicity by irradiation of peripheral nerves is suggested.
MeSH terms
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Adolescent
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Child
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Female
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Humans
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Male
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Neoplasms / drug therapy
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Neoplasms / radiotherapy
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Peripheral Nervous System Diseases / chemically induced*
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Peripheral Nervous System Diseases / etiology
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Radiotherapy / adverse effects*
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Vincristine / adverse effects*