Abstract
We described the detailed characterization and high-resolution mapping of nine herpes simplex virus type 1 mRNAs encoded in EcoRI fragment I. Four of these mRNAs are partially colinear and encode the same sized polypeptide in vitro. Nucleotide sequence analysis of the DNA around the 5' ends of these mRNAs suggested that the larger may encode a small (ca. 100-dalton) polypeptide not resolvable by in vitro translation.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Base Sequence
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DNA Restriction Enzymes
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DNA, Viral / genetics
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Deoxyribonuclease EcoRI
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Genes, Viral
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Nucleic Acid Hybridization
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Protein Biosynthesis
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RNA, Messenger / genetics*
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RNA, Viral / genetics*
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Simplexvirus / genetics*
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Viral Proteins / genetics*
Substances
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DNA, Viral
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RNA, Messenger
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RNA, Viral
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Viral Proteins
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DNA Restriction Enzymes
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Deoxyribonuclease EcoRI