Abstract
Three hundred and eleven cases of rectal cancer received treatment according to the protocol of a cooperative randomized study. Preoperative irradiation improved three-year survival rates, particularly, in node-negative patients. In node-positive patients, frequency of relapse dropped from 30.0 +/- 8.5 to 5.7 +/- 3.9% when surgical treatment was supplemented by pre- and postoperative irradiation or drug therapy.
Publication types
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Clinical Trial
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English Abstract
MeSH terms
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Adenocarcinoma / drug therapy
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Adenocarcinoma / radiotherapy
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Adenocarcinoma / surgery
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Adult
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Aged
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Clinical Trials as Topic
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Cobalt Radioisotopes / therapeutic use
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Combined Modality Therapy
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Female
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Fluorouracil / therapeutic use
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Humans
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Male
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Middle Aged
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Random Allocation
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Rectal Neoplasms / drug therapy
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Rectal Neoplasms / radiotherapy
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Rectal Neoplasms / surgery*
Substances
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Cobalt Radioisotopes
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Fluorouracil