This report gives an updated account of the phase II and III bladder studies conducted by the Genito-Urinary Cooperative Group of the EORTC. All phase II studies screen for activity in patients with measurable advanced disease. All phase III studies are randomized studies aimed at controling the recurrence rate of superficial bladder tumors. This long term planning on chemotherapy and chemoprevention will be continued in an orderly fashion and expanded with the evaluation of radiotherapy, surgery and/or immunology regimens for tumor control in the near future.