Digital tomosynthesis represents a new technique for digital manipulation of data acquired during a single tomographic sweep. With the aid of a computer, data can be processed to yield images in any parallel plane of the body. This technique allows rapid tomographic studies requiring a much lower radiation dose to the patient. Dynamic studies such as angiotomography are feasible, and application to digital subtraction intravenous angiography is also possible with this technique. Early experience with clinical application in patient studies is presented.