Amauromine, a new vasodilator. Taxonomy, isolation and characterization

J Antibiot (Tokyo). 1984 Nov;37(11):1320-23. doi: 10.7164/antibiotics.37.1320.

Abstract

Amauromine is a new alkaloid with vasodilating activity obtained from the culture broth of Amauroascus sp. No. 6237. Its molecular formula was determined to be C32H36N4O2 on the basis of elementary analysis and high resolution mass spectroscopic measurement. It has low toxicity in mice.

MeSH terms

  • Alkaloids / isolation & purification*
  • Alkaloids / pharmacology
  • Animals
  • Aorta / drug effects
  • Ascomycota / classification
  • Ascomycota / metabolism*
  • Chemical Phenomena
  • Chemistry
  • Fermentation
  • In Vitro Techniques
  • Indoles*
  • Male
  • Rats
  • Rats, Inbred Strains
  • Vasodilator Agents / isolation & purification*
  • Vasodilator Agents / pharmacology

Substances

  • Alkaloids
  • Indoles
  • Vasodilator Agents
  • amauromine