Abstract
New thioureas and ureas with an interesting anti-ulcer and antisecretory activity are disclosed. The chemical synthesis, determination of the structure, and structure-activity relationships of the compounds are discussed.
MeSH terms
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Animals
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Anti-Ulcer Agents / chemical synthesis
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Anti-Ulcer Agents / pharmacology*
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Chemical Phenomena
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Chemistry
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Gastric Juice / metabolism*
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Male
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Parasympatholytics
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Piperidines / chemical synthesis
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Piperidines / pharmacology*
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Rats
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Rats, Inbred Strains
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Stomach Ulcer / chemically induced
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Stomach Ulcer / prevention & control
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Structure-Activity Relationship
Substances
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Anti-Ulcer Agents
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Parasympatholytics
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Piperidines