Platelet MAO activity and the dexamethasone suppression test in depressed patients

Am J Psychiatry. 1983 Sep;140(9):1231-3. doi: 10.1176/ajp.140.9.1231.

Abstract

Platelet monoamine oxidase (MAO) activity and postdexamethasone cortisol levels were determined in 26 depressed patients. The incidence of cortisol nonsuppression and the mean postdexamethasone cortisol levels were significantly higher in patients with high MAO activity than in those with low MAO activity.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Blood Platelets / enzymology*
  • Depressive Disorder / blood
  • Depressive Disorder / diagnosis*
  • Dexamethasone*
  • Female
  • Humans
  • Hydrocortisone / blood
  • Male
  • Middle Aged
  • Monoamine Oxidase / blood*

Substances

  • Dexamethasone
  • Monoamine Oxidase
  • Hydrocortisone